Differential plus polarographic determination of submicrogram quantities of carmustine and related compounds in biological samples.
نویسندگان
چکیده
A polarographic method was developed to determine the antineoplastic agent carmustine and other nitrosoureas, such as N-methyl-N-nitrosourea and N-cyclohexyl-N-nitrosourea, in biological fluids at levels well below 1 microgram/ml or g. The stability of carmustine in different media was investigated to prevent losses during administration or assay. Examples of nitrosourea determination in biological samples are given.
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عنوان ژورنال:
- Journal of pharmaceutical sciences
دوره 67 8 شماره
صفحات -
تاریخ انتشار 1978